Nilotinib

CAS 641571-10-0

Overview

Nilotinib, sold under the brand name Tasigna, is a medication used to treat chronic myelogenous leukemia which has the Philadelphia chromosome. It may be used both in initial cases of chronic phase CML as well as in accelerated and chronic phase CML that has not responded to imatinib. It is taken by mouth. Cas No:

Anant Labs manufacture and furnish high quality Nilotinib impurities for global markets. Our Nilotinib EP Impurities are used by API manufacturers and fully integrated pharmaceutical companies worldwide.

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Nilotinib

CAS 641571-10-0In Stock

Technical Data

CAS641571-10-0

Mol. FormulaC₂₈H₂₂F₃N₇O

Mol. Weight529.526 g/mol

IUPAC4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide

SMILESCC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5

InChIInChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)

InChI KeyHHZIURLSWUIHRB-UHFFFAOYSA-N

Synonyms

Nilotinib641571-10-0AMN 107AMN-107nilotinibum4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamideDanzitenNSC-7475994-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamideDTXSID5042663