Mertansine
CAS 139504-50-0
Overview
Mertansine is a potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at sub-nanomolar concentrations
Anant Labs manufacture and furnish high quality Mertansine impurities for global markets. Our Mertansine EP Impurities are used by API manufacturers and fully integrated pharmaceutical companies worldwide.
Technical Data
New Cat. No.ANTPRD7584
Old Cat. No.ANT-MTS-000
CAS139504-50-0
Mol. FormulaC35H48ClN3O10S
Mol. Weight738.29 g/mol
IUPAC[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(3-sulfanylpropanoyl)amino]propanoate
SMILESC[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCS)C)\C)OC)(NC(=O)O2)O
InChIInChI=1S/C35H48ClN3O10S/c1-19-10-9-11-26(46-8)35(44)18-25(47-33(43)37-35)20(2)31-34(4,49-31)27(48-32(42)21(3)38(5)28(40)12-13-50)17-29(41)39(6)23-15-22(14-19)16-24(45-7)30(23)36/h9-11,15-16,20-21,25-27,31,44,50H,12-14,17-18H2,1-8H3,(H,37,43)/b11-9+,19-10+/t20-,21+,25+,26-,27+,31+,34+,35+/m1/s1
InChI KeyANZJBCHSOXCCRQ-FKUXLPTCSA-N
Synonyms
N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansineMertansine139504-50-0Maytansinoid DM 1Mertansine (DM1)maytansinoid DM1DM 1DM1MFCD28398157DDZ29HGH0E