Lovastatin
CAS 75330-75-5
Overview
Lovastatin, sold under the brand name Mevacor among others, is a statin medication, to treat high blood cholesterol and reduce the risk of cardiovascular disease. Its use is recommended together with lifestyle changes. It is taken by mouth
Anant Labs manufacture and furnish high quality Lovastatin impurities for global markets. Our Lovastatin EP Impurities are used by API manufacturers and fully integrated pharmaceutical companies worldwide.
Technical Data
CAS75330-75-5
Mol. FormulaC24H36O5
Mol. Weight404.547 g/mol
IUPAC[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
SMILESCC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C
InChIInChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI KeyPCZOHLXUXFIOCF-BXMDZJJMSA-N
Synonyms
lovastatin75330-75-5mevinolinMevacorAltoprevMevlorSivlorAltocorMK-803Monacolin KLovastatine6alpha-MethylcompactinLovastatinaMevinacorLovastatinum [Latin]6-alpha-MethylcompactinLovastatinumMK 803DTXSID50207849LHU78OQFDNSC-758662(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoateL-154803C10AA022beta,6alpha-Dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoateDTXCID50784(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrateCHEBI:403036-MethylcompactinNSC633781Lovastatinum (Latin)(1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))-2-Methylbutanoic acid 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester(S)-2-Methylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one1,2,6,7,8,8a-Hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutyoxy)-1-naphthaleneheptanoic acid delta-lactoneButanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))-1 alpha-Isomer Lovastatin6 Methylcompactin(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxooxan-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoateMK803alpha-Isomer Lovastatin, 1ML-530BMevinacor 10Mevinacor 40((1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxooxan-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) (2S)-2-methylbutanoate(S)-2-Methylbutyric acid, 8-ester with (4R,6R)-6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl]ethyl]tetrahydro-4-hydroxy-2H-pyran-2-oneLovastatin, 1 alphaRefChem:5964(2S)-2-Methylbutanoic Acid, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl Ester(8-(2-(4-hydroxy-6-oxooxan-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate616-212-7((1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxooxan-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) (2R)-2-methylbutanoateLovalordNergadanArteinLovastatine [French]Lovastatina [Spanish]LovalipHipovastinLovasterolCholestraClosterolColevixHipolipLestatinLipivasLipofrenLovastinLozutinPascholRodatinRovacorTecnolipTeroltratBelvasLipdipTaucorbutanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-Lovastatin [USAN]MLS000069585Lovastatin (Standard)6.alpha.-MethylcompactinMSD 803MFCD00072164SMR000058779(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoateC24H36O5(S)-(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methylbutanoateHSDB 6534NCGC00023509-03Liposcler6 alpha-MethylcompactinRextatMonakolin KLovastatin (Mevacor)(+)-mevinolin(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-tetrahydropyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoateMevacor (TN)CHEMBL503Lovastatin & PrimycinLovastatin (USP/INN)SR-05000001880UNII-9LHU78OQFDSimvastatin EP Impurity EBRN 3631989TancorCCRIS 8092Mevinacor;Lipofren;Nergadan;Mevacor;Lovastatin CRSMonacolin K;1cqpLovastatin [USAN:USP:INN:BAN](2S)-2-METHYLBUTANOIC ACID (1S,3R,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-3,7-DIMETHYL-8-(2-((2R,4R)-TETRAHYDRO-4-HYDROXY-6-OXO-2H-PYRAN-2-YL)ETHYL)-1-NAPHTHALENYL ESTER(2S)-2-Methylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl esterButanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (2S)-Prestwick_819CAS-75330-75-5Mevinolin (lovastatin)LOVASTATIN [MI]LOVASTATIN [INN]Opera_ID_1578Prestwick0_000516Prestwick1_000516Prestwick2_000516Prestwick3_000516Spectrum3_001873Spectrum5_001294Lovastatin (MK-803)LOVASTATIN [HSDB]LOVASTATIN [VANDF]EC 616-212-7LOVASTATIN [MART.]SCHEMBL3136LOVASTATIN [USP-RS]LOVASTATIN [WHO-DD]US9115116, lovastatinBIDD:PXR0113BSPBio_000471BSPBio_001265BSPBio_00334674133-25-8cid_53232MLS001055358MLS006011867US9353061, LovastatinaBIDD:GT0749DivK1c_001032SPECTRUM1503977SPBio_002392BPBio1_000519GTPL2739Lovastatin - Bio-X trade markMEGxm0_000398orb1309414orb3139800LOVASTATIN [ORANGE BOOK]ACon0_000534ACon1_000390BDBM34168HMS503O05HY-N0504RKBio1_001032KBio3_002848LOVASTATIN [EP MONOGRAPH]Simvastatin impurity, lovastatin-NINDS_001032GLXC-06458HMS1569H13HMS1792O07HMS1923O13HMS1990O07HMS2089M06HMS2093O03HMS2096H13HMS2236F07HMS3039N16HMS3259F10HMS3268C03HMS3403O07HMS3412H19HMS3676H19HMS3713H13HMS3884B03LOVASTATIN [USP MONOGRAPH]Pharmakon1600-01503977ADVICOR COMPONENT LOVASTATINALBB-027272HY-N0504MK-803; LOVALIP; MEVACORMSK10235Tox21_110888Tox21_201475Tox21_300268BBL024473CCG-39627EBC-02080NSC758662NSC779704s2061SBB080686STK801953AKOS005267139Lovastatin for peak identification CRSLovastatin; Simvastatin EP Impurity ETox21_110888_1CS-1990DB00227FH24950KS-1082Mevinolin from Aspergillus sp., powderNC00713NSC 758662NSC-633781NSC-779704IDI1_001032NCGC00023509-04NCGC00023509-05NCGC00023509-06NCGC00023509-07NCGC00023509-08NCGC00023509-09NCGC00023509-10NCGC00023509-11NCGC00023509-13NCGC00023509-14NCGC00023509-16NCGC00023509-25NCGC00254157-01NCGC00259026-01AC-13961BL164644Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (2S)-G226SMR000673570SBI-0051881.P002CS-0694830L0214NS00000544SIMVASTATIN IMPURITY E [EP IMPURITY]EN300-52515C07074D00359M02056AB00052400-17AB00052400_18AB00052400_19Mevinolin from Aspergillus sp., >=98% (HPLC)Q417740SR-01000000123SR-01000000123-3SR-05000001880-1SR-05000001880-2BRD-K09416995-001-06-8BRD-K09416995-001-21-7BRD-K09416995-001-38-1BRD-K09416995-001-39-9BRD-K09416995-001-40-7Mevacor;Monacolin K;mevinolin;6-alpha-MethylcompactinSIMVASTATIN IMPURITY, LOVASTATIN- [USP IMPURITY]Z754931258(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-8-(2-((4R,6R)-4-hydroxy-2-oxo-2H-pyran-6-yl)ethyl)-3,7-dimethylnaphtyl(S)-2-methylbutyrat(S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-((3R,5R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl ester1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl 2-methylbutanoate1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate8-[2-((2R,4R)-4-hydroxy-6-oxo(2H-3,4,5-trihydropyran-2-yl))ethyl](1S,7S,8S,3R, 8aR)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthyl (2S)-2-methylbutanoateButanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-- oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))-BUTANOIC ACID, 2-METHYL-, 1,2,3,7,8,8A-HEXAHYDRO-3,7-DIMETHYL-8-(2-(TETRAHYDRO-4-HYDROXY-6-OXO-2H-PYRAN-2-YL)ETHYL)-1-NAPHTHALENYL ESTER, (1S-(1.ALPHA.(R*),3.ALPHA.,7.BETA.,8.BETA.(2S*,4S*),8.ALPHA..BETA.))-