Indomethacin
CAS 53-86-1
Overview
Indometacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation. It works by inhibiting the production of prostaglandins, endogenous signaling molecules known to cause these symptoms. Cas No:
Anant Labs manufacture and furnish high quality Indomethacin impurities for global markets. Our Indomethacin EP Impurities are used by API manufacturers and fully integrated pharmaceutical companies worldwide.
Technical Data
New Cat. No.ANTPRD1602
Old Cat. No.ANT-IND-00
CAS53-86-1
Mol. FormulaC19H16ClNO4
Mol. Weight357.79 g/mol
IUPAC2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
SMILESCC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
InChIInChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
InChI KeyCGIGDMFJXJATDK-UHFFFAOYSA-N
Synonyms
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acidindomethacinindometacin53-86-1IndomethacineIndometacineIndocidMetindolReumacideIndomethazineIdomethineImbrilonMikametanIndacinMobilanTannexAmunoInteban spArtrinovoConfortidIndomecolIndomethacinumMetartrilMethazineArtracinArtriviaDolovinIndomedIndomeeIndopticIndoptolInflazonInfrocinMetacenMezolinSadoreumInacidLausitIndo-rectolminIndo-tablinenIndometacynaIndometicinaDurametacinIndo-LemmonIndometacinumIndometacinaAconipIndocin SrOsmosin2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acidIndomet 140Rheumacin LA1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-TivorbexIndomodIndolar SR1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acidNCI-C56144FLAM2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acidDTXSID9020740XXE1CET956NSC-7570611-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acidIndole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-CHEBI:49662N-p-Chlorbenzoyl-5-methoxy-2-methylindole-3-acetic acid(1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-yl)acetic acidNSC-77541alpha-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acidDTXCID507401-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acidKwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure(1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETIC ACIDNSC77541IndodermIndoflexIndolarLedmecinRimacidPardelprin mrArtracin srIndocid ret2-(1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl)acetic acidIndomethacin ERMaximet srIndo-paedIndocid-rSlo-indo(1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acidBerlind 75 retIndotard mr 75Indomax-25Indomax-75 srFlexin-25 continusFlexin-50 continusFlexin-75 continusRefChem:5905Indomethacin Extended-releaseC01EB03M01AB01M02AA23S01BC011-(4-chlorobenzoyl)-5-methoxy-2-methyl-1-H-indole-3-acetic acid200-186-5IndocinCatlepDolcidiumElmetacinIndomethineIndorektalIndoxenVonumIndo-phlogontChibro-amuno1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acidMFCD00057095CCRIS 3502HSDB 3101Indometacin [INN]Indomethacin (Indocid, Indocin)CHEMBL6IMNMLS0000694021-(p-Chlorobenzoyl)-2-methoxy-3-methyl-1H-indole-3-acetic Acid2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1h-indol-3-yl}acetic acids1723CAS-53-86-1NCGC00015562-18IndmethacineIndomethancinArthrexinBonidinBonidonIndamethMiametanSMR000058195IndomoFlexin continusHicinChrono-indicidChrono-indocidIndometacyna [Polish]2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acidBonidon GelIndometicina [Spanish]Dolcidium PLIndo-SprayIndometacine [INN-French]Indometacinum [INN-Latin]Indometacina [INN-Spanish]1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acidIndonolInnamitInteban2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetic acidIndocin-SRIndochron E-RIndocin (TN)Aconip (TN)Indomethacin (USP)Indocid (pharmaceutical)SR-01000000014EINECS 200-186-5Indomethacin & MAP-30Indomethacin [USAN:USP]UNII-XXE1CET956BRN 0497341Indocollyre1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-Indole-3-acetic acidArtracin;Imbrilon;Indocid;Indocin;Indomed;Indometacin CRS2-{1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methylindol-3-yl}acetic acidFlexin;4kykPrestwick_597Indomethacin (GMP)USANOpera_ID_56Spectrum_000919Tocris-17081z9hIndomethacin (Standard)1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure [German]1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico [Spanish]Prestwick0_000272Prestwick1_000272Prestwick2_000272Prestwick3_000272Spectrum2_000970Spectrum3_000468Spectrum4_000018Spectrum5_000868INDOMETACIN [JAN]INDOMETHACIN [MI]Lopac-I-7378Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy [Polish]Indometacin (Indomethacin)Epitope ID:613433MolMap_000032UPCMLD-DP023EC 200-186-5I 7378Indometacin (JP18/INN)INDOMETHACIN [HSDB]INDOMETHACIN [USAN]SCHEMBL9300INDOMETACIN [MART.]INDOMETHACIN [VANDF]Lopac0_000692Oprea1_686105BSPBio_000144BSPBio_001149BSPBio_002176INDOMETACIN [WHO-DD]INDOMETACIN [WHO-IP]KBioGR_000395KBioGR_000489KBioSS_000489KBioSS_0013995-22-05-00239 (Beilstein Handbook Reference)MLS001074194MLS006011845BIDD:GT0132DivK1c_000271INDOMETHACIN [USP-RS]SPECTRUM1500350SPBio_000979SPBio_002363BPBio1_000160GTPL1909orb1310593Indometacin impurity mixture CRSIndomethacin, >=99% (TLC)SCHEMBL11563010SCHEMBL29353712UPCMLD-DP023:001BDBM17638CGIGDMFJXJATDK-UHFFFAOYSA-HMS500N13KBio1_000271KBio2_000489KBio2_001399KBio2_003057KBio2_003967KBio2_005625KBio2_006535KBio3_000897KBio3_000898KBio3_001396MSK7168NINDS_000271Bio2_000405Bio2_000885HMS1362I11HMS1568H06HMS1792I11HMS1920F21HMS1990I11HMS2089N19HMS2091N09HMS2095H06HMS2231J10HMS3262K05HMS3268A14HMS3374F07HMS3403I11HMS3414N13HMS3430L03HMS3649K17HMS3655O04HMS3678N11HMS3712H06HMS3747K21HMS3884E08HMS5079F18INDOMETACIN [EP MONOGRAPH]Indomethacin - Bio-X trade markINDOMETHACIN [ORANGE BOOK]Pharmakon1600-01500350MDA37708INDOMETHACIN [USP MONOGRAPH]Tox21_113109Tox21_201791Tox21_300266Tox21_500692AC-532CCG-40186EBC-04405HB4422HY-14397GHY-14397RINDOMETACINUM [WHO-IP LATIN]NSC757061SBB057417STL257874AKOS000592893Indometacin; Acemetacin EP Impurity BTox21_113109_1AT13679DB00328FI24585Indometacin 1.0 mg/ml in AcetonitrileKS-5255LP00692NSC 757061SDCCGSBI-0050670.P005IDI1_000271IDI1_002160NCGC00015562-01NCGC00015562-02NCGC00015562-03NCGC00015562-04NCGC00015562-05NCGC00015562-06NCGC00015562-07NCGC00015562-08NCGC00015562-09NCGC00015562-10NCGC00015562-11NCGC00015562-12NCGC00015562-13NCGC00015562-14NCGC00015562-15NCGC00015562-16NCGC00015562-17NCGC00015562-19NCGC00015562-20NCGC00015562-21NCGC00015562-22NCGC00015562-24NCGC00015562-25NCGC00015562-40NCGC00024135-02NCGC00024135-04NCGC00024135-05NCGC00024135-06NCGC00024135-07NCGC00024135-08NCGC00024135-09NCGC00024135-10NCGC00024135-11NCGC00024135-12NCGC00024135-13NCGC00024135-14NCGC00024135-15NCGC00254075-01NCGC00259340-01NCGC00261377-01BI166166BP-30207HY-14397NCI60_041708O-Desmethyl-des-4-chlorobenzoylacemetacinSBI-0050670.P004ACEMETACIN IMPURITY B [EP IMPURITY]DB-052413AB00052022EU-0100692I0655NS00000217ST50320042SW196768-5EN300-16807Indomethacin, meets USP testing specificationsBIM-0050670.0001C01926D00141S00108AB00052022-20AB00052022-21AB00052022_23AB00052022_24F358171L000959Q409231SR-01000000014-2SR-01000000014-4SR-01000000014-6BRD-K57222227-001-06-1BRD-K57222227-001-18-6BRD-K57222227-001-27-7BRD-K57222227-001-28-5BRD-K57222227-001-29-3BRD-K57222227-001-30-1SR-01000000014-10SR-01000000014-16Z567848961-p-chlorobenzoyl-2-methyl-5-methoxyindol-3-acetic acid1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indoleacetic acid1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-acetic acid1-(p-chlorobenzyl)-5-methoxy-2-methylindole-3-acetic acid1-(4-chloro-benzoyl)-5-methoxy-2-methyl-3-indolyl-acetic acid1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indole-acetic acid1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indol acetic acidIndomethacin, European Pharmacopoeia (EP) Reference StandardN-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acidIndomethacin, United States Pharmacopeia (USP) Reference Standard.alpha.-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid #1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid & MAP-301H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl- (9CI)2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2 methylindol-3-yl}acetic acid2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2methylindol-3-yl}acetic acidIndole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl- (8CI)Indomethacin, Pharmaceutical Secondary Standard; Certified Reference MaterialInChI=1/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)